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David Bilkey (Department of Psychology and Brain Health Research Centre, University of Otago, Dunedin, New Zealand) | Changes in hippocampal plasticity, activity and memory in a rat model of schizophrenia

When Jun 07, 2016
from 05:15 PM to 06:45 PM
Where BCF Lecture Hall, Hansastr. 9a
Contact Name Robert Schmidt
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Abstract

Schizophrenia directly affects about 1% of the population. Many individuals with schizophrenia exhibit memory deficits and problems in constructing, maintaining, and processing the context of a situation. There is also evidence that the hippocampus, a region of the brain associated with memory and contextual processing, has structural and biochemical abnormalities in individuals with schizophrenia. In this seminar I describe the use of a neurodevelopmental model of a schizophrenia risk factor to investigate whether an early environmental insult (maternal immune activation) is associated with abnormal neural activity in the adult hippocampus. A key question is how any abnormalities in neural processing might underlie deficits in contextual and memory processing.

 

Supported by

Bernstein Center Freiburg | PhD Program BrainDiscDeutscher Akademischer Austauschdienst DAADFederal Ministery of Education and ResearchCarl Zeiss FoundationNeurexNeuroCampusEU Development FundEU InterregNeurAGBrainLinks BrainTools

 

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