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Synthetic brain rhythms | Scientists used optogenetic stimulation to induce slow brain rhythms in vivo

Synthetic brain rhythms | Scientists used optogenetic stimulation to induce slow brain rhythms in vivo

August 21, 2018: Researchers from the Bernstein Center Freiburg and the Massachusetts Institute of Technology used an innovative optogenetic stimulation paradigm to evoke synthetic brain rhythms in vivo. In contrast to conventional optogenetic stimulations protocols that rely on light pulses, this protocol employed continuously modulating light intensities to mimic normal brain rhythms using a new implant. These findings have recently been published in Journal of Neural Engineering, and open up possibilities to cell-specifically dissect the neuronal circuits underlying pathological and physiological slow brain oscillations.

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Taking an electrical fingerprint of nerve cells

Taking an electrical fingerprint of nerve cells

Scientists from the Bernstein Center Freiburg and their colleagues from Norway present a framework for the automatized and objective localization and classification of neurons recorded with state-of-the-art high-resolution multi-electrode arrays

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Generating knowledge and sharing it with society

Generating knowledge and sharing it with society

This has been the motivation with which Jonathan Schiefer has conducted his research. Now the Bernstein Center Freiburg would like to congratulate him on his successful dissertation on "Inference of multi-scale connectivity in the brain".

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Reciprocity of social influence: Who do we take advice from and why?

Reciprocity of social influence: Who do we take advice from and why?

New insights in social decision making: our influence on others highly affects how much influence we take from them

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Informative Video about the Bernstein Center Freiburg

Informative Video about the Bernstein Center Freiburg

Are you interested in briefly seeing what our work is about? Then, watch our video on our Youtube Channel. We wish to thank the Bernstein Network Computational Neuroscience, who instigated this video production and made it financially possible.

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Artificial neural networks learn to control biological neuronal networks

Artificial neural networks learn to control biological neuronal networks

It is already common practice to influence brain activity by means of deep brain stimulation – which means through electrical impulses via implanted electrodes – for example in patients suffering from Parkinson's Disease or epilepsy. The effects, however, are still poorly understood. "I send an electrical pulse in, usually in a strictly predetermined rhythm, but even though it works, I'm not sure what the brain does with it and how much depends on the neuronal activity going on in the background," explains Dr. Sreedhar Kumar from the Bernstein Center Freiburg and the Department of Microsystems Technology (IMTEK). "There is no feedback so I cannot react to possible changes in brain activity. It's an open loop." But what if the stimulating system were able to do just that and find the optimal way to stimulate at any moment? This is where the interdisciplinary research project of the Freiburg Neurorobotics Lab, the Bernstein Center Freiburg and the IMTEK comes in.

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Summa cum laude for Renato Duarte

Summa cum laude for Renato Duarte

The Bernstein Center Freiburg would like to congratulate Renato Duarte on his doctorate. He defended his thesis on "State-dependent processing in spiking neural networks" with excellence.

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Which network caused the traffic? | A new approach to infer effective connectivity from fMRI signals

Which network caused the traffic? | A new approach to infer effective connectivity from fMRI signals

An interdisciplinary research team from the Bernstein Center Freiburg and the University Medical Center Freiburg have devised a new approach to infer networks from functional magnetic resonance imaging (fMRI) signals. The new procedures can identify both the direction and the sign of effective interactions in large networks with high fidelity and reliability.

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Mesial temporal lobe epilepsy: Large-scale changes of network oscillations?

Mesial temporal lobe epilepsy: Large-scale changes of network oscillations?

Mesial temporal lobe epilepsy (MTLE) is the most common form of focal epilepsies in adults and frequently resistant to anti-epileptic medication. It is characterized by recurrent seizures, pathological restructuring of the hippocampal formation and is often accompanied by cognitive deficits, in particular by impairments of spatial navigation and memory. Changes in a certain type of oscillatory network activity are being discussed as a possible cause of these memory deficits, which in turn were seen in connection with structural changes in the hippocampus. New studies by PhD student Antje Kilias and co-workers from the Bernstein Center Freiburg, the Dept. of Microsystems Engineering, University of Freiburg and the Freiburg University Medical Center, however, suggest other conclusions.

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Alternative view on structural plasticity in neuronal networks: Hebbian associative properties can also result from firing rate homeostasis

Alternative view on structural plasticity in neuronal networks: Hebbian associative properties can also result from firing rate homeostasis

Scientists from the Bernstein Center Freiburg demonstrated that Hebbian association in neuronal networks can also emerge from homeostatic plasticity, which is normally thought to exclusively stabilize neuronal activity.

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New Neuroscience Landing Page online

New Neuroscience Landing Page online

Good news for all those who would like to get a quick overview of the neuroscientific research sector in Freiburg. The Bernstein Center Freiburg has created a "Landing Page" to be found under www.neuro.uni-freiburg.de.

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In Conversation: Neuroscience meets Art

In Conversation: Neuroscience meets Art

Uploading the brain to a computer - is this possible? This was the theme of a discussion between Prof. Stefan Rotter, Managing Director of the Bernstein Center Freiburg, and the audiovisual artist Lina Hermsdorf at the invitation of Freiburg's Kunstverein. The "Artist's Talk" is part of the current exhibition "Immortalism". Listen to the whole podcast now.

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"Analysis of Parallel Spike Trains" in high demand

"Analysis of Parallel Spike Trains" in high demand

Rotter and Grün make SpringerLink’s 50 percent most downloaded books list

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Neurotechnology on trial

Neurotechnology on trial

Examining the usability of four implants for simultaneous recording and manipulation of neural circuits

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Desperately Seeking Rooms and Apartments!

Desperately Seeking Rooms and Apartments!

The Bernstein Center Freiburg is currently looking for rooms and apartments to accommodate students of the Joint Master Neuroscience course (JMN) in June and July

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Carola Haas receives Alfred Hauptmann Award for Epilepsy Research 2017

Carola Haas receives Alfred Hauptmann Award for Epilepsy Research 2017

Best epileptological research papers of German-speaking countries awarded at trinational conference

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