The Bernstein Center for Computational Neuroscience Freiburg

Announcement for the next
BCCN Seminar
Prof. Dr. Peter Fromherz
Department of Membrane and Neurophysics
MPI Biochemistry

Neuron-Semiconductor Interfacing ? its Nature and Implementation
Thursday, April 6th, 2006
Lecture Hall (ground floor)
BCCN building
Hansastraße 9A
79104 Freiburg
It is a challenge to join semiconductor chips and neuronal systems on a microscopic level with the goal to develop hybrid processors for scientific, medical and technological applications. On the biological side, we consider the three levels of ion channels, of individual nerve cells from snails and rats and of tissue from rat brain. We analyze the structure and the electrical resistance of the cell-silicon contact with luminescent dyes. To elucidate the mechanism of interfacing, we study the interaction of recombinant sodium and potassium channels with capacitors and transistors of simple silicon chips. On the basis of these results, we implement the two-way interfacing of silicon chips with individual nerve cells, with small neuronal networks and with brain tissue. CMOS chips with thousands of interfacing sites are applied to obtain time-resolved maps of for recording and stimulation on the level of single cells, of small neuronal networks and of brain tissue.
The talk is open to the public. Guests are cordially invited!