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B4: NeurOnline: System for on-site/on-line monitoring of neuronal population activity

Stefan RotterB

B = Bernstein Center for Computational Neuroscience

Scientific background

 

It is now standard to record the activity of large neuronal populations, both in behaving animals using acute or implanted electrode arrays, and in brain slices or tissue cultures using substrate-integrated multi-electrode arrays. Various types of signals are regularly recorded with these techniques: single-unit (SUA) and multi-unit (MUA) spike trains, local field potentials (LFP) and electro-corticograms (ECoG).

 


Objectives

The aims of this project are (I) to select appropriate methods to characterize the various neuronal signals and adapt them for online use, (II) to establish a test system that emulates realistic conditions during recordings, and (III) to develop an interfacing framework that allows adapting the new software to alternative recording systems. Finally, (IV) the applicability of this approach will be demonstrated in an in vivo setting.
Our plan is to make the new software freely available to all BCNT/NNCN members, as well as to the wider scientific community.

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