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Philipp Schnepel

PhD Student

 


Research Project

  • BCCN-Leiterpool: Influence of columnar and laminar synapctic connectivity patterns on spontaneous and stimulus-induced network dynamics in rat sensory neocortex

 

Research Topics

  •  Physiology of long-range horizontal projections and their impact on network dynamics

 

Techniques

  • Acute slice preparation (rats)
  • simultaneous somatic/dendritic patch-clamp, sharp recordings, paired recordings
  • dynamic photostimulation
  • connectivity mapping
  • fluorescence imaging, histology, staining and reconstructions (Neurolucida)
  • Data analysis / programming
  • hardware interfacing
     

CV

Academic Background

  • 2008-present: PhD-studies at the Bernstein Center Freiburg and Neurobiology & Biophysics, University of Freiburg, Germany
  • 2000-2008: Diploma studies (MSc) in Biology, Neurobiology & Biophysics, University of Freiburg, Germany


Research Positions

  • Student Assistant Neurobiology & Biophysics, University of Freiburg, Germany 
    Acute slice preparation and electrophysiology, custom MATLAB-based software development, database maintenance


Teaching Experience

  • 2012-present: ‘Introduction to Neurobiology – Practical Course Muscle Physiology of Crickets'
  • 2007-present: ‘Measurement and Analysis of Neuronal Activity'
  • 2007-present: ‘Electrophysiology in Living Brain Slices’
  • 2009-2011: Co-supervision of Master-students
     

Invited Talks

  • Schnepel P, ‘Abundance of long-range connections shapes local network dynamics’ BCCN Meeting Freiburg: Dynamics of Neuronal Systems, Freiburg, Germany, March 2013
     

Collaborations

  • Prof. Alex Thomson School of Pharmacy, London, UK (9 months stay in 2009)
    Sharp-electrode recordings in adult rats, histology and reconstructions
  • Dr. Arvind Kumar Bernstein Center Freiburg, Germany
    Data analysis, large-scale neuronal network models, correlations
  • Dr. Martin Nawrot Bernstein Center for Computational Neuroscience, Freie Universität Berlin, Germany
    Data analysis, biophysical models, network dynamics
  • Miha Pelko Institute of Adaptive & Neural Computation, University of Edinburgh, UK
    Data analysis, compartmental NEURON models

 

Publications

Articles 

  • Schnepel P, Kumar A, Aertsen A and Boucsein C (2013) Physiology and impact of horizontal connections in rat neocortex. (in preparation)
  • Boucsein C, Nawrot M, Schnepel P and Aertsen A (2011) Beyond the cortical column: abundance and physiology of horizontal connections imply a strong role for inputs from the surround. Front. Neurosci. (2011) Apr 1;5:32 / doi: 10.3389/fnins.2011.00032
  • Nawrot M, Schnepel P, Aertsen A and Boucsein C (2009) Precisely timed signal transmission in neocortical networks with reliable intermediate-range projections. Front. Neural Circuits (2009) 3:1 doi:10.3389/neuro.04.001.2009


Abstracts

  • Schnepel P, Nawrot M, Aertsen A and Boucsein C (2012) Long-range connectivity profile of L5B pyramidal neurons implies strong role for horizontal projections. 8th FENS Forum of European Neuroscience, Barcelona, Spain, July 2012
  • Zohar M, Schnepel P, Aertsen A and Boucsein C (2012) Projection patterns onto different compartments of layer V pyramidal neurons in rat neocortex. 8th FENS Forum of European Neuroscience, Barcelona, Spain, July 2012
  • Zohar M, Schnepel P, Aertsen A and Boucsein C (2011). Compartment-specific projection patterns onto pyramidal cells in rat neocortex. Front. Comput. Neurosci. Conference Abstract: BC11: Computational Neuroscience & Neurotechnology Bernstein Conference & Neurex Annual Meeting 2011. doi: 10.3389/conf.fncom.2011.53.00127
  • Schnepel P, Nawrot M, Aertsen A and Boucsein C (2011) Physiological properties of non-local projections onto layer 5 pyramidal neurons. 9th Göttingen Meeting of the German Neuroscience Society, Göttingen, Germany, March 2011, n° T23-8C
  • Zohar M, Schnepel P, Aertsen A and Boucsein C (2011) Differential dendritic and somatic input mapping in layer V pyramidal neurons. 9th Göttingen Meeting of the German Neuroscience Society, Göttingen, Germany, March 2011, n° T7-10A
  • Schnepel P, Nawrot M, Aertsen A and Boucsein C (2010). Number, reliability and precision of long-distance projections onto neocortical layer 5 pyramidalneurons. Front. Comput. Neurosci. Conference Abstract: Bernstein Conference on Computational Neuroscience. doi: 10.3389/conf.fncom.2010.51.00110

 

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